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Cell proliferation in cancer : regulatory mechanisms of neoplastic cell growth / edited by L. Pusztai, C.E. Lewis E. Yap.

Contributor(s): Material type: TextTextPublication details: Oxford ; New York : Oxford University Press, 1995.Description: xxi, 397 p. : ill. ; 24 cmISBN:
  • 0198547919 (hardback)
Subject(s): DDC classification:
  • 616.994/071 20
LOC classification:
  • RC268.5 .C39 1995
NLM classification:
  • QZ 202 C3927 1995
Contents:
1. Introduction: cell proliferation and carcinogenesis / L. Pusztai and K. Cooper -- 2. The cell cycle / V. Sorrentino -- 3. Oncogenes and tumour-suppressor genes / M. A. Piris, M. Sanchez-Beato, R. Villuendas and J. C. Martinez -- 4. Oncogenes and tumour-suppressor genes as prognostic indicators in the development of human tumours / J. K. Field and D. A. Spandidos -- 5. The role of cytokines in tumour progression / M. S. Naylor and F. R. Balkwill -- 6. Abnormal growth factor networks in neoplasia / E. Tahara, W. Yasui and H. Yokozaki -- 7. The fibroblast growth factor family: multifunctional regulators of cell proliferation / W. H. Burgess and J. A. Winkles -- 8. The potential application and limitation of cytokine/growth factor manipulation in cancer therapy / M. Okada and T. Kishimoto -- 9. Neuropeptide growth factors: signalling pathways and role in cancer / E. Rozengurt -- 10. Hormonal regulation of cancer cell growth / H. Wasan and J. Waxman --
11. Retinoids in neoplasia / S. A. Ross, L.-C. Chen, N. Darwiche and L. M. De Luca -- 12. Metastasis: secondary proliferation in distant organs / D. Tarin -- 13. Apoptosis: a role in neoplasia? / C. D. Gregory -- 14. Cell differentiation and its role in carcinogenesis and therapy / R. A. Rifkind, J. Michaeli, V. M. Richon, H. Kiyokawa, X. Busquets, L. Leng and P. A. Marks.
Summary: This book comprises a number of state-or-the-art reviews written by leading scientists. Each chapter gives a concise overview of specific intra- and intercellular events which regulate the proliferation of neoplastic cells, and the established or potential clinical implications of these developments. The topics have been selected to cover major recent advances in our understanding of the molecular events which govern cell division.Summary: It is expected that students, scientists, and clinicians working in the fields of oncology, pathology, and molecular/cellular biology would find this volume invaluable as a stimulating source of information.
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Holdings
Item type Current library Call number Copy number Status Date due Barcode Item holds
Loan - Normal on open shelf Loan - Normal on open shelf UOE Main Library Open shelf RC268.5 .C39 1995 (Browse shelf(Opens below)) 20014975 Available 20014975
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Includes bibliographical references and index.

1. Introduction: cell proliferation and carcinogenesis / L. Pusztai and K. Cooper -- 2. The cell cycle / V. Sorrentino -- 3. Oncogenes and tumour-suppressor genes / M. A. Piris, M. Sanchez-Beato, R. Villuendas and J. C. Martinez -- 4. Oncogenes and tumour-suppressor genes as prognostic indicators in the development of human tumours / J. K. Field and D. A. Spandidos -- 5. The role of cytokines in tumour progression / M. S. Naylor and F. R. Balkwill -- 6. Abnormal growth factor networks in neoplasia / E. Tahara, W. Yasui and H. Yokozaki -- 7. The fibroblast growth factor family: multifunctional regulators of cell proliferation / W. H. Burgess and J. A. Winkles -- 8. The potential application and limitation of cytokine/growth factor manipulation in cancer therapy / M. Okada and T. Kishimoto -- 9. Neuropeptide growth factors: signalling pathways and role in cancer / E. Rozengurt -- 10. Hormonal regulation of cancer cell growth / H. Wasan and J. Waxman --

11. Retinoids in neoplasia / S. A. Ross, L.-C. Chen, N. Darwiche and L. M. De Luca -- 12. Metastasis: secondary proliferation in distant organs / D. Tarin -- 13. Apoptosis: a role in neoplasia? / C. D. Gregory -- 14. Cell differentiation and its role in carcinogenesis and therapy / R. A. Rifkind, J. Michaeli, V. M. Richon, H. Kiyokawa, X. Busquets, L. Leng and P. A. Marks.

This book comprises a number of state-or-the-art reviews written by leading scientists. Each chapter gives a concise overview of specific intra- and intercellular events which regulate the proliferation of neoplastic cells, and the established or potential clinical implications of these developments. The topics have been selected to cover major recent advances in our understanding of the molecular events which govern cell division.

It is expected that students, scientists, and clinicians working in the fields of oncology, pathology, and molecular/cellular biology would find this volume invaluable as a stimulating source of information.

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